What pain relievers can be taken with Lexapro

Painkillers for side effects Take ibuprofen, paracetamol and Co after corona vaccination?

From Klaus Zintz
Klaus Zintz (Zz)profile
 

Complaints after the corona vaccination can be treated with medication. Why you should exercise caution and under no circumstances should you take medication such as ibuprofen, paracetamol or aspirin in advance?

Painkillers for side effects?

Means that relieve pain and reduce fever are often taken to alleviate the typical side effects such as fever or headache after a corona vaccination - if they occur at all. Means like Paracetamol as well as so-called nonsteroidal anti-inflammatory drugs (NSAIDs), to which Ibuprofen, aspirin, and diclofenac belong.

After the second vaccination, the side effects are which are also typical of a flu-like infection, often stronger than the first time. They show that the immune system is active and the body is preparing itself to defend itself against a possible infection.

However, some experts believe that these agents could adversely affect the vaccination responseby interfering with the formation of antibodies, for example. There were indications of this in earlier smaller studies with other vaccines against diphtheria, tetanus and whooping cough, for example.

Do not take ibuprofen and paracetamol preventively

For example, in a study published in the “Lancet” in 2009, the precautionary intake of paracetamol clearly reduced the number of children who had a fever of 38 degrees and higher after the first vaccination. However, it was the antibody response is also weakened by the vaccination. A comprehensive study on this topic is not yet available.

In the information sheet on corona vaccinations, on which the Robert Koch Institute also worked, it says: “In case of pain and fever after the vaccination pain reliever / antipyretic medication (e.g. paracetamol) may be taken.“

This is also recommended, for example, by the US health authority CDC. Linked to this, however, is the urgent request that these antipyretic and pain relievers be used not to be taken as a preventive measure before the vaccination in anticipation of possible side effects.

It is also pointed out that that possibly also for other medical reasons these funds should be avoidedfor example on ibuprofen because of allergic reactions or severe kidney disease. In addition, there is the well-known advice to take care of your body after the vaccination.

Vaccination side effects: when to see a doctor?

If side effects occur after the vaccination, it should also careful attention should be paid to their type and duration. Headache, for example, is one of the typical flu-like symptoms that should go away after a day or two at the latest.

Keep the side effects though longer than three days or if severe headaches, dizziness or visual disturbances reappear after this time, see chapYou should definitely consult a doctor, recommends the Society for Thrombosis and Hemostasis Research (GTH).

Anticoagulants and AstraZeneca

As we know after the recent discussion about the Astrazeneca vaccine, in very rare cases the vaccination could lead to a dangerous cerebral vein thrombosis that must be treated. Recently, Greifswald researchers uncovered a possible mechanism for the development of such thromboses. Accordingly, it occurred in four patients with a cerebral vein thrombosis after vaccination with the Astrazenca vaccine for the formation of antibodiesthat are directed against blood platelets (thrombocytes).

These antibodies then cause a massive activation of the platelets, which can lead to thrombosis, i.e. a blood clot in the brain. Doctors compare this with an already known complication of the administration of the anticoagulant heparin, heparin-induced thrombocytopenia (HIT). Regardless of the fact that there could be other causes for this complication after vaccination with Astrazenca, the GTH recommends Carry out detailed investigations in the event of side effects. In addition, anticoagulation with heparins should be avoided "until (autoimmune) HIT" has been ruled out - provided the clinical situation permits.

Great Astrazeneca study

In the meantime, the results of a large-scale phase III clinical trial of the Astrazeneca vaccine have also become known. About 32,500 people in Chile, Peru and the USA took part. Against the background of the recently reported thrombosis events after vaccinations, according to Astrazeneca, a group of experts among the study participants also searched specifically for indications of thrombosis.

Among the approximately 21,600 people who had been vaccinated at least once, however, there was no evidence of possible connections. Overall, in this phase III study, the vaccine was also shown to be very effective in older people over 65 years of age. Across all age groups, the vaccine protects 79 percent against a corona infection with symptoms and 100 percent against a severe course that requires hospitalization. Astrazenca now also wants to apply for approval in the USA.